Two passengers died and 63 others were injured in two separate accidents on the Gulu and Masaka highways. Police by last evening had not determined the cause of the accidents, which happened six hours apart on Tuesday night.
A Kampala-bound Gaaga Coach bus moving from Koboko Town overturned at around 4:30am at Katalemwa in Wakiso District, killing businessman Apollo Mawa on the spot. Another man only identified as Basegezi later died on the way to the hospital, police said.
"The bus failed to negotiate a corner before it rolled over several times," Mr Henry Kalulu, deputy Metropolitan Police spokesman, said, adding: "So far 38 people have been admitted with serious injuries."
He said heavy fog in the wee hours of the morning probably blurred the driver's visibility, causing him to veer off the road just 15 kilometres to the final destination the city centre.
Mr James Nyakuni, the owner and managing director of Gaaga Bus Company, who had just returned from a business trip to Burundi, said they were yet to find out why the bus crashed but "it is unfortunate we lost our esteemed customers".
Another bus heading to the Rwanda capital, Kigali, reportedly crashed into a stationary truck at about 10pm, injuring 25 people. The latest road accidents have triggered questions about safety of night commuters.